Propafenone Hydrochloride

Propafenone Hydrochloride is a medication that belongs to the class of drugs known as antiarrhythmics. It is used primarily to treat certain types of abnormal heart rhythms, specifically those originating in the upper chambers of the heart (atria). The drug works by stabilizing the electrical activity within the heart, which helps to regulate and maintain a normal heartbeat.

Mechanism of Action:

• Propafenone exerts its effects by blocking specific sodium channels and beta-adrenergic receptors in the heart tissue. This dual action helps to slow down the conduction of electrical impulses through the atria, thereby reducing the likelihood of arrhythmias.

  
  

Indications:

• It is commonly prescribed for the management of supraventricular tachycardia (SVT), including atrial fibrillation and atrial flutter. In some cases, it may also be used off-label for other types of cardiac arrhythmias under close medical supervision.

  
  

  English name:	Propafenone Hydrochloride
  English alias:	Propafenone hydrochloride [USAN:JAN]; 2'-(2-Hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenone hydrochloride; Arythmol; Baxarytmon; Fenoprain; Pronon; Propafenon hydrochlorid; Propafenon hydrochlorid [German]; Propafenone hydrochloride; Rhythmonorm; Rythmol; Rythmol SR; Rytmonorm; SA 79; UNII-33XCH0HOCD; WZ 884; 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride; 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride; Propiophenone, 2'-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-, hydrochloride; 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride (1:1); 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride
  CAS Number:	34183-22-7
  EINECS Number:	251-867-9
  Molecular formula:	C21H28ClNO3
  Molecular weight:	377.9049
  InChI：	InChI=1/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H
  Boiling point:	519.6°C at 760 mmHg
  Flash point:	268°C
  Steam pressure:	1.27E-11mmHg at 25°C