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Labetalol hydrochloride is a medication that belongs to the class of drugs known as beta-blockers. It is used primarily to treat hypertension (high blood pressure) and angina pectoris (chest pain). The drug works by blocking both beta1 and beta2 adrenergic receptors, which helps to lower blood pressure and reduce heart rate.
Mechanism of Action
Labetalol hydrochloride exerts its effects by selectively blocking beta1 adrenergic receptors in the heart and beta2 adrenergic receptors in the smooth muscles of the blood vessels. This dual action leads to a reduction in heart rate and force of contraction, as well as vasodilation (widening of the blood vessels), which collectively lowers blood pressure and reduces the workload on the heart.
Indications
It is commonly prescribed for the management of hypertension (high blood pressure) and angina pectoris (chest pain). In some cases, it may also be used off-label for other cardiovascular conditions under close medical supervision.
| English name: | Labetalol Hydrochloride |
| English alias: | 5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)salicylamidehydrochlori;5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-salicyChemicalbooklamidhydroch;ah5158a;amipress;ipolab;labelol;5-[1-HYDROXY-2-[(1-METHYL-3-PHENYLPROPYL)-AMINO]ETHYL]SALICYLAMIDEHYDROCHLORIDE;LABETALOLHCL |
| CAS Number: | 32780-64-6 |
| EINECS Number: | 251-211-1 |
| Molecular formula: | C19H25CIN2O3 |
| Molecular weight: | 362.8505 |
| Melting point: | 187-189°C |
