Roxatidine Acetate Hydrochloride

Roxatidine acetate hydrochloride is a medication that belongs to the class of drugs known as histamine H2-receptor antagonists. It is primarily used to treat conditions related to excessive stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The drug works by blocking the action of histamine at the H2 receptors in the stomach, which reduces acid production.

Mechanism of Action

• Roxatidine acetate hydrochloride exerts its effects by competitively inhibiting the action of histamine at the histamine H2 receptors on the parietal cells in the stomach. This inhibition decreases the secretion of hydrochloric acid, thereby reducing gastric acidity and allowing the stomach and esophagus to heal from damage caused by excess acid.

  
  

Indications

• It is commonly prescribed for the management of gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. In some cases, it may also be used off-label for other gastrointestinal conditions under close medical supervision.